HPLC method with electrochemical detection on gold electrode for simultaneous determination of different antimicrobial agents in cosmetics

Electrochemical determination of acetaminophen in different pharmaceutical forms with gold nanoparticles carbon paste electrode.

The electrochemical behavior of acetaminophen on a gold nanoparticles (nAu) carbon paste electrode (CPE) was investigated. Cyclic voltammograms of acetaminophen with nAu-CPE exhibited two well defined redox waves for anodic and cathodic peak, respectively. The oxidation reaction of acetaminophen was studied with differential pulse voltammetry (DPV) and square wave voltammetry (SWV). The oxidati...

Determination of Clinically Relevant Compounds using HPLC and Electrochemical Detection with a Boron-Doped Diamond Electrode

Electrochemical Approach for Determination of Tertahydrozoline HCl Using Gold nanoparticles Electrode

The electrochemical behavior of tetrahydrozoline (THZ) was explored by cyclic voltammetry and differential pulse voltammetry. A well-defined peak at 915 mV using gold nanomodified electrode (AuNPts/CP) in presence of sodium dodecyl sulphate (SDS) was detected. Different buffers, pH and scan rates on oxidation peak current were studied. Linear calibration curve was achieved in the range of 1.99×...

Electrochemical Determination of Food Preservative Nitrite with Gold Nanoparticles/p-Aminothiophenol-Modified Gold Electrode

Due to the negative impact of nitrate and nitrite on human health, their presence exceeding acceptable levels is not desired in foodstuffs. Thus, nitrite determination at low concentrations is a major challenge in electroanalytical chemistry, which can be achieved by fast, cheap, and safe electrochemical sensors. In this work, the working electrode (Au) was functionalized with p-aminothiophenol...

Development of an RP-HPLC-UV method for simultaneous detection of nimodipine and its metabolite in cerebrospinal fluid of rat

A rapid, simple and reproducible HPLC method was developed and validated for the analysis of nimodipine (NM) and/or its metabolite, oxidized nimodipine (OX–NM) in rat cerebrospinal fluid (CSF) and artificial CSF. The NM and OX–NM were eluted in less than 10 min with no interferences from the endogenous CSF peaks. Analysis was carried out on a Eurospher Performance (RP-C18, 250 × 4.6 mm) column ...